Nexium Esomeprazole


Nexium the patrimonial name Esomeprazole is the inhibitor of the proton pump used for processing of GERD (an illness of a reflux), an ulcer of a duodenal gut and erosion. Inhibitors of the proton pump - group of drugs. Their main action is reduction of acid of gastric juice (acid of gastric juice) production. Experts say that proton inhibitors of the pump - the strongest and effective inhibitors of gastric juice in the market today. Nexium also is used for prevention of stomach ulcers in the patients receiving long-term therapy of NSAID and for patients with an illness Krone with gastro enteric ulcers.
Nexium Esomeprazole online as all proved worked effectively in fight against many main reasons capable to become erectile dysfunctions. Cheap patrimonial Nexium, such as they is recommended for people of all age who very much try to support their installation during a floor. Thus, if you suffer from a moderate case capable to erectile straight dysfunctions, then it is valid - anything to be cares about in general. Possibilities consist that this condition will naturally clean independently if you give it enough time. Nexium is gastric juice have strong chemicals that the stomach can usually deal, but not thin membranes of a gullet. GERD which remains not cured can cause finally damage of a fabric to the lining of a gullet bringing. Without treatment Nexium can become very serious condition. With treatment, however, the patient can make a complete recovery. According to the pharmaceutical company, AstraZeneca, producers and distributors of Nexium:  Patients can't tell without medical care, whether there are at them erosion in a gullet and how serious they, Even in moderate cases of heartburn, the damage put with heartburn, probably, already took place, Patients with eroziyny ezofagity which take Nexium in general, do a complete recovery during four - eight weeks.. For an injection for children at the age of 1 month or it is more for short-term processing of GERD when it not possible and not corresponding to operate oral therapy. (Contact article), Stomach ulcers appear either in a stomach or in a duodenal gut (an ulcer of a duodenal gut). The majority of these ulcers is caused a helicobacter, a bacterium which exists in the sour environment of a stomach. Patients who are allergic on esomeprazole or other benzimidazole medicine, such as mebendazole or albendazole, shouldn't take Nexium. Patients with a serious illness of a liver should tell to their doctor before to take Nexium. Paitents with low levels of magnesium of blood should tell to their doctor before to take Nexium.

Buy Nexium Esomeprazole


Nexium Esomeprazole is used to treat a disease of a gastroezofagealny reflux (GERD), a condition in which the acid countercurrent from a stomach causes heartburn and possible injury of a gullet (a pipe between a throat and a stomach). Esomeprazole is used to consider GERD signs, to allow a gullet to cure, and to prevent further injury of a gullet. Esomeprazole also is used to reduce chance that people who take nonsteroid anti-inflammatory preparations will fall ill with ulcers (wounds in a stomach or intestines lining). It also is used with other drugs to consider and prevent return of the stomach ulcers caused by a certain type of bacteria (H. pylori). Esomeprazole also is used to consider conditions in which a stomach makes too much acid, such as Zollindzher-Allison's syndrome. Esomeprazole is in a class of the drugs called proton inhibitors of the pump. It works, reducing amount of the acid made in a stomach.
Nexium Esomeprazole became the delayed release a capsule (long action) to take for a mouth or to open, mix up with water and to give through a nutritious tube and as a granule, to mix up with water and to take for a mouth or to give through a nutritious tube. Esomeprazole usually undertakes once a day at least in 1 hour prior to food. When esomeprazole is used to consider certain conditions in which a stomach does too much acid, it is taken twice a day. Take esomeprazole within the same time every day. Follow instructions on the label of the instruction carefully and ask, that your doctor or the pharmacist explained any part which you don't understand. Take esomeprazole precisely as it is directed. Don't take more or less it or take it more often than or during longer period, than ordered by your doctor, or declared on a package.
You can buy Nexium online in special internet drugstores every time. Swallow of the whole capsules; don't split, chew or break them. If you can't swallow of a capsule, place 1 tablespoon of cool, soft apple sauce in an empty sphere. Open one esomeprazole a capsule and carefully balls on apple sauce. Mix balls with apple sauce and swallow of all tablespoons of apple sauce and a ball mix immediately. Don't chew balls in apple sauce. Don't save balls and apple sauce for later use. For you it is important to hold the written list of all instruction and sold without the recipe (released without the recipe) drugs which you accept, just as any products, such as vitamins, minerals or other food additives. You should bring this list with you each time when you visit the doctor or if you allow in hospital. It is also important information to bear with you in case of emergency situations.

Nexium


Esomeprazole tablet

What is this medicine?

ESOMEPRAZOLE prevents the production of acid in the stomach. It is used to treat gastroesophageal reflux disease (GERD), ulcers, certain bacteria in the stomach, and inflammation of the esophagus. It can also be used to prevent ulcers in patients taking medicines called NSAIDs.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • liver disease
  • an unusual or allergic reaction to esomeprazole, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth. Swallow the capsules whole with a drink of water. Do not crush, break or chew. The capsules can be opened and the contents sprinkled on applesauce. Do not crush the contents into the food. This medicine works best if taken on an empty stomach at least one hour before a meal. Take your medicine at regular intervals. Do not take your medicine more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

  • ampicillin
  • digoxin
  • iron salts
  • itraconazole, ketoconazole, voriconazole, or other prescription medicines for fungus or yeast infections
  • warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

It can take several days before your stomach pains get better. Check with your doctor or health care professional if your condition does not start to get better or if it gets worse.

What side effects may I notice from this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing problems
  • chest pain or tightness
  • dark urine
  • unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
  • diarrhea or constipation
  • dry mouth
  • headache
  • nausea/vomiting
  • stomach pain or gas
This list may not describe all possible side effects.

Where should I keep my medicine?

Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and moisture. Throw away any unused medicine after the expiration date.

Esomeprazole (Nexium)

Why is this medication prescribed?

Esomeprazole is used to treat gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus (the tube between the throat and stomach). Esomeprazole is used to treat the symptoms of GERD, allow the esophagus to heal, and prevent further damage to the esophagus. Esomeprazole is also used to decrease the chance that people who are taking nonsteroidal anti-inflammatory drugs (NSAIDs) will develop ulcers (sores in the lining of the stomach or intestine). It is also used with other medications to treat and prevent the return of stomach ulcers caused by a certain type of bacteria (H. pylori). Esomeprazole is also used to treat conditions in which the stomach produces too much acid such as Zollinger-Ellison syndrome. Esomeprazole is in a class of medications called proton pump inhibitors. It works by decreasing the amount of acid made in the stomach.

How should this medicine be used?

Esomeprazole comes as a delayed-release (long-acting) capsule to take by mouth or to open, mix with water, and give through a feeding tube and as granules to mix with water and take by mouth or give through a feeding tube. Esomeprazole is usually taken once a day at least 1 hour before a meal. When esomeprazole is used to treat certain conditions in which the stomach makes too much acid, it is taken twice a day. Take esomeprazole at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take esomeprazole exactly as directed. Do not take more or less of it or take it more often than or for a longer period of time than prescribed by your doctor or stated on the package.

Swallow the capsules whole; do not split, chew, or crush them. If you cannot swallow the capsule, put 1 tablespoon of cool, soft applesauce in an empty bowl. Open one esomeprazole capsule and carefully sprinkle the pellets onto the applesauce. Mix the pellets with the applesauce, and swallow the entire tablespoonful of the applesauce and pellet mixture immediately. Do not chew the pellets in the applesauce. Do not save the pellets and applesauce for later use.

To mix the granules, follow these steps:

  1. Place 1 tablespoon (15 mL) of water into a cup.

  2. Open the esomeprazole packet and empty the granules into the cup containing the water.

  3. Stir the granules into the water and leave the mixture alone for 2 to 3 minutes so that it will thicken.

  4. Stir the mixture again, and drink all of the mixture within 30 minutes.

  5. If any material remains in the cup after drinking, add some more water and stir. Drink all of the mixture immediately.

The granules and the contents of the capsules can both be given through a feeding tube. If you have a feeding tube, ask your doctor or pharmacist how you should take the medication. Follow those directions carefully.

It may take several weeks or longer for you to feel the full benefit of esomeprazole. Call your doctor if your symptoms worsen or do not improve during this time. Continue to take esomeprazole even if you feel well. Do not stop taking esomeprazole without talking to your doctor.

If your condition does not improve or gets worse, call your doctor.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking esomeprazole,

  • tell your doctor and pharmacist if you are allergic to esomeprazole, dexlansoprazole (Dexilant), lansoprazole (Prevacid), omeprazole (Prilosec, Zegerid), pantoprazole (Protonix), rabeprazole (AcipHex), any other medications, or any of the ingredients in esomeprazole capsules or powder. Ask your pharmacist for a list of the ingredients.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin); certain antifungals such as ketoconazole (Nizoral) and voriconazole (Vfend); cilostazol (Pletal); diazepam (Valium); digoxin (Digitek, Lanoxicaps, Lanoxin); diuretics ('water pills'); iron supplements; and certain medications for human immunodeficiency virus (HIV) such as atazanavir (Reyataz), nelfinavir (Viracept), and saquinavir (Invirase). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had a low level of magnesium in your blood or liver disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking esomeprazole, call your doctor.
  • you may take antacids with esomeprazole. If you feel you need an antacid, ask your doctor to recommend one and to tell you when and how to take it.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Esomeprazole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • headache

  • diarrhea

  • nausea

  • gas

  • stomach pain

  • constipation

  • dry mouth

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

  • blisters or peeling skin

  • hives

  • rash

  • itching

  • difficulty breathing or swallowing

  • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs

  • hoarseness

  • irregular, fast, or pounding heartbeat

  • excessive tiredness

  • dizziness

  • lightheadedness

  • muscle spasms

  • uncontrollable shaking of a part of the body

  • seizures

People who take proton pump inhibitors such as esomeprazole may be more likely to fracture their wrists, hips, or spine than people who do not take one of these medications. The risk is highest in people who take high doses of one of these medications or take them for one year or longer. The risk may also be higher in people who are 50 years of age or older. Talk to your doctor about the risk of taking esomeprazole.

Esomeprazole may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

Nexium ESOMEPRAZOLE - Buy Nexium Online

Nexium Esomeprazole helps in reducing the amount of acid produced within the stomach. Generic Nexium (Esomeprazole) is also used for treating symptoms of gastroesophageal reflux disease (GERD). Also it is used to treat conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. It can also be used to quicken the healing process of erosive esophagitis.
Patients suffering from gastric ulcer caused by infection with helicobacter pylori or by the use of nonsteroidal anti-inflammatory drugs can be given Generic Nexium.
Generic Nexium - Esomeprazole can also be used for other medical purposes than those listed above.
Nexium Medication :
DO NOT use this Nexium Medication if you are allergic to Nexium or to any other benzimidazole medication such as albendazole (Albenza), or mebendazole (Vermox). Before taking Nexium Medicine, you are advised to inform your doctor about your medical history, especially if you ever had any liver problem. Certain medication conditions demand a treatment which is a combination of Nexium Medicine along with some other antibiotic. In such cases you should take all the prescribed medications as advised by your doctor or medical care provider. Read the instructions mentioned on the medication guide properly and follow STRICTLY. DO NOT change to dosage pattern of Nexium Medication unless advised by your doctor.
FDA has placed this medication in Category B, which states that this medication is not expected to cause any harm to unborn baby. However, you MUST inform your doctor if you plan to become pregnant or if you are pregnant during the course of the treatment. Since it is unknown whether or not Nexium passes into breast milk, consult with your doctor before using this medication especially if you are breast-feeding a baby.
Nexium Side Effects :
Nexium can cause some allergic side effects but the intensity depends on the individual. However, you MUST ask for immediate medical help if you experience any of the following allergic Nexium Side Effects

Nexium (esomeprazole magnesium)

Nexium (esomeprazole magnesium)

Company: AstraZeneca
Approval Status: Approved February 2001
Treatment for: Duodenal ulcer disease, erosive esophagitis, and gastroesophageal reflux disease
Areas: Gastrointestinal

General Information

Nexium has been approved by the FDA for the relief of heartburn and other symptoms associated with gastroesophageal reflux disease (GERD) and for the healing of erosive esophagitis, a potentially serious condition associated with GERD. The FDA also approved Nexium for maintenance of healing of erosive esophagitis and, in combination with amoxicillin and clarithromycin, for the eradication of Helicobacter pylori infection in patients with duodenal ulcer disease.

Nexium is derived from Prilosec (omeprazole). Prilosec contains a racemic mixture of the D- and L- forms (isomers) of omeprazole. Nexium contains only one of the isomers. Both Prilosec and Nexium are known as proton pump inhibitors.

As many as 25 million adults experience heartburn on a daily basis. Although heartburn is the most common symptom of GERD, the condition is also often marked by other symptoms - such as a sour taste in the mouth or difficulty swallowing - related to the backing up of harsh stomach acid into the esophagus. When this acid reflux damages the lining of the esophagus, it may lead to a potentially more serious condition called erosive esophagitis that can lead to narrowing or ulceration of the esophagus.


Clinical Results

Four multicenter, double-blind, randomized trials evaluated the healing rates of Nexium 40 mg, Nexium 20 mg, and omeprazole 20 mg in subjects with endoscopically diagnosed erosive esophagitis. Healing rates were evaluated at week four and eight. At week eight, healing rates were higher with Nexium treatment compared to omeprazole in all four studies.

Two multicenter, randomized, double-blind, placebo-controlled 4-arm trials evaluated the long-term maintenance of healing of erosive esophagitis. The trials included subjects with endoscopically confirmed, healed erosive esophagitis, and they evaluated Nexium 40 mg, 20 mg and 10 mg once-daily over six months of treatment. Subjects remained in remission significantly longer and the number of recurrences of erosive esophagitis was significantly less in subjects treated with Nexium compared to placebo.

Nexium's effectiveness in the resolution of GERD symptoms was evaluated in two multicenter, randomized, double-blind, placebo-controlled trials. These trials were conducted in a total of 717 subjects, and they compared four weeks of treatment with Nexium 20 mg or 40 mg once daily versus placebo. The percentage of subjects who were symptom-free of heartburn was significantly higher in the Nexium groups compared to placebo at all follow-up visits (weeks 1, 2 and 4).

In three European symptomatic GERD trials, no significant treatment related differences were observed between Nexium 20 mg and 40 mg and omeprazole 20 mg.

Nexium in combination with amoxicillan and clarithromycin was tested in two multicenter, randomized, double-blind trials for the eradication of Helicobacter pylori (H. pylori) in subjects with duodenal ulcer disease. H. pylori eradication rates at four weeks post-therapy were significantly higher in the Nexium plus amoxicillin and clarithromycin group than in a Nexium plus clarithromycin or Nexium alone group.


Side Effects

Side effects reported with Nexium use include (but are not limited to) the following:


  • Headache
  • Diarrhea
  • Abdominal pain

Safety and effectiveness have not yet been established in pediatric patients.

Please consult your physician for further information on side effects or to discuss the individual appropriateness of Nexium treatment.


Mechanism of Action

Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of H+/K+-ATPase in the gastric parietal cell. By acting specifically on the proton pump, esomeprazole blocks the final step in acid production, thus reducing gastric acidity. This effect is dose-related up to a daily dose of 20 to 40 mg and leads to inhibition of gastric acid secretion. (Nexium Prescribing Information)


Additional Information

Nexium is produced in a delayed-release capsule formulation, with dosages of 20 mg or 40 mg.

Nexium (esomeprazole)


Nexium (esomeprazole)

Nexium Description

Esomeprazole magnesium is the active ingredient in Nexium. Esomeprazole is a proton pump inhibitor sold under different brand names and Nexium is a popular drug. This drug is produced and marketed by AstraZeneca for treating gastroesophageal reflux disease (GERD), peptic ulcer disease, dyspepsia and Zollinger – Ellison syndrome. The medication brings down acid secretion by way of inhibiting ATPase in gastric parietal cells. This thereby prevents gastric acid formation. Nexium can provide a day’s relief from the symptoms of acid reflux disease. It can heal erosions caused on the esophagus and therefore it is called the Healing Purple Pill.
Nexium should not be kept within the reach of children. Keep the lid of bottle tightly secured after each use. Do not change the original package of the medicine and keep it away from moisture and sunlight. Nexium should be stored at room temperature. You should take this medication only as prescribed by your doctor. Multiple daily doses and dosages for an extended period of time can result in harmful effects such as bone fractures.

Conditions treated by Nexium

Nexium is basically used to heal erosive esophagitis where it is indicated for treating symptomatic and healing resolution of clinically confirmed erosive esophagitis (EE). It is also used for maintaining healing and resolution of EE. Erosive Esophagitis is a potentially serious condition that refers to damage of the esophagus. This happens largely due to damage caused by stomach acid eating away esophageal lining. GERD and associated symptoms such as heartburns and others are treated using Nexium. Symptoms of this acid reflux disease include consistent heartburn for two or more days in a week in spite of dietary changes and treatment. The medication is also used in pediatric use for treating kids and adolescents in the age group of 1 and 17 years. However, in infants below 1 year of age, no studies have proven effectiveness of the drug. Safety in administering Nexium to babies is also not established.

Nexium Dosage Information

a.) Typical Dosage Recommendations

Nexium is available in the United States as delayed release capsules and in Australia and Canada as delayed release tablets. These contain esomeprazole magnesium in strengths of 40 mg and 20mg. Esomeprazole sodium is used for intravenous infusion or injection. Preparations meant for oral use are enteric coated because the drug rapidly degrades in your stomach due to acidic conditions. Nexium is generally taken at least one hour before you take your meals. The drug is usually administered for about 4 to 8 weeks only. Thereafter, your doctor will decide whether a second course is needed or not. Four to eight weeks is the time required to heal and maintain.
Every dose of Nexium should be taken with one full glass of water. Patients suffering from GERD in the case of healing of erosive esophagitis should take a 20mg or 40mg dose every day for a period of 4 to 8 weeks as prescribed. In cases of healing esophagitis maintenance, 20mg dose can be taken daily. 20mg every day for 4 weeks is the recommended dosage for treating symptomatic gastroesophageal reflux disorder. Short term treatments for GERD in pediatric patients (12 to 17 year olds), 20mg or 40mg of the drug is administered for up to 8 weeks and in 1 to 11 year olds, 10mg is given once every day for 8 weeks. The medicine in the capsule can be taken out and swallowed without chewing. It can also be administered through a nasogastric feeding tube.

b.) Missing a Dose

If you have missed to take Nexium, take it the next time you remember. But if it is already time for your next dose, skip the missed one. Taking extra medicine to compensate for the missed ones should be avoided.

c.) Overdosing

If you think you have been overdosed by Nexium, contact Poison Helpline or get emergency medical attention to avert possible side effects. Symptoms of overdosing can include convulsions, co-ordination loss, tremors, shortness of breath, flushing, sweating, dry mouth, nausea, rapid heartbeats, blurred vision, drowsiness, headache and confusion.

Nexium Warnings

If you find yourself allergic to esomeprazole or benzimidazole drugs such as mebendazole or albendazole, avoid taking Nexium. If you suffer from a severe liver disease, special tests or Nexium dose adjustments may be needed. Nexium has an ability to amplify your chances of a bone fracture in the spine, wrist or hip. Such issues have occurred in individuals who have taken the drug for an extended period of time or in high doses or are 50 years or older. If you have low bone mineral density and suffer from osteopenia or osteoporosis, inform your doctor before taking Nexium. Nexium has not been known to cause any harm to unborn babies. However, if you have conceived or are planning to conceive, inform your doctor prior to taking the medication. Similarly, breast feeding mothers should consult their doctors before taking Nexium although no studies have proved the effect of the drug on babies through breast milk.

Nexium Side Effects

If you are allergic to Nexium, you are bound to experience one of the following symptoms: swelling of throat, lips, tongue and face, breathing difficulties and hives. Other possible side effects to this drug can include dry mouth, constipation, gastric trouble, nausea, diarrhea, drowsiness, abdominal pain and headache. Medical attention is needed when you experience one or more of certain strong side effects such as strong allergic reactions (unusual hoarseness, tightness in your chest, itching, hives and rashes), unusual tiredness, unusual bleeding or bruising, severe stomach pain or cramps, diarrhea, peeling and blistered skin, sore throat, chills, fever, dark urine, chest pain and bone pain. Several studies have demonstrated the fact that Nexium results in increased risk of hip, wrist or spinal bone fracture.